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Philippe Ascher is confirmed dead at the age of 86.

Why did Philippe Ascher have to die now? We may never know.
⚱️⚱️⚱️⚱️⚱️⚱️⚱️⚱️⚱️⚱️⚱️⚱️⚱️⚱️
'The world will miss Philippe💔
What did Philippe Ascher do?
Philippe was best known as a French neuroscientist.
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Philippe Ascher
Born(1936-06-28)28 June 1936
Died4 October 2022(2022-10-04) (aged 86)
NationalityFrench
CitizenshipFrance
Alma materÉcole normale supérieure
Spouse
(m. 1967)
Awards
Scientific career
FieldsNeuroscience
InstitutionsCNRS
Philippe Ascher (28 June 1936 – 4 October 2022) is a French neuroscientist who was professor emeritus at the Université Paris Diderot. He has devoted his research mainly to the characterization of certain neurotransmitter receptors. He has been a corresponding member of the French Academy of Sciences since 1990.
Contents
1 Biography
1.1 Education
1.2 Career
1.3 Personal life
2 Awards and honours
2.1 Diplomas, titles and awards
2.2 Extra-academic distinctions
3 References
Biography
Education
Ascher was a student at the École normale supérieure from 1955 to 1959 and passed the Agrégation of biology in his final year, a highly competitive postgraduate examination which serves as a national ranking of students. Then he devoted his thesis to a problem of organization of nerves (the analysis of the circuits involved in the startle reaction of the anaesthetized cat to chloralose). He became a Doctor of Science in 1965.
Career
Philippe Ascher is interested in the ionic mechanisms associated with the action of neurotransmitters. On Aplysian neurons, he studied the inhibitory and excitatory effects of dopamine, and the rapid excitatory actions of acetylcholine. In the study of mammalian neurons, he participated in the characterization of L-glutamate receptors, particularly those activated by N-methyl-D-aspartic acid (NMDA receptors). He discovered the role of Mg ions in the functioning of these receptors, and the modulating role of glycine. He then studied the role of NMDA receptors in the plasticity of cerebellar synapses.
In 1965 he met a post-doctoral student named JacSue Keohe, whom he married in 1967 and with whom he had a scientific collaboration throughout his career.
In 1971 at the École normale supérieure (ENS), he founded the Neurobiology Laboratory, of which he was director until 2001. Then in 1992, still at the ENS, he succeeded Pierre Joliot as head of the Biology Department (until 1999).
In 1992 he won the Richard Lounsbery Award jointly with Henri Korn for "their discoveries of the mechanisms of synaptic transmission. Philippe Asher furthered knowledge regarding the properties of glutamate receptors which play an important role in trials, and Henri Korn brought to light the elementary liberation of neurotransmitter in quanta form in the central nervous system of vertebrates."
Ascher's later research focused on a synapse in the spinal cord that uses both acetylcholine and glutamate.
In 2003, having reached official retirement age with his wife JacSue, he joined Alain Marty who heads the Laboratory of Cerebral Physiology at the University of Paris-Descartes. Since 2019, he has been Professor Emeritus at the SPPIN laboratory (Saint-Pères Paris Institute for Neurosciences) of the French National Centre for Scientific Research, also at the University of Paris-Descartes.
Personal life
Ascher married in 1967 the American researcher JacSue Kehoe (died in 2019) with whom he had two sons. He died on 4 October 2022, at the age of 86.
Awards and honours
Diplomas, titles and awards
1965: PhD Thesis
1992: Richard-Lounsbery Award from the National Academy of Sciences and the French Academy of Sciences
Extra-academic distinctions
1989: elected to the pan-European Academy of Humanities, Letters, Law, and Sciences Academia Europaea (physiology and neuroscience section)
1990: Knight of the Legion of Honor
1990: Elected correspondent of the French Academy of Sciences (Molecular and Cellular Biology, Genomics Section)
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