Dirk Bootsma is confirmed dead at the age of 84.

If you treat everyone like Dirk Bootsma did, you will also be remembered fondly.
Recent portrait of Dirk Bootsma
'The world will miss Dirk💔
What did Dirk Bootsma do?
Dirk was best known as a Dutch geneticist.
How did Dirk Bootsma die?
Dirk Bootsma's death was likely due to a broken heart.
If this is wrong, please click here to correct.

Send for review
Dirk Bootsma
Dirk Bootsma
Born(1936-05-23)23 May 1936
Died5 October 2020(2020-10-05) (aged 84)
Alma materUtrecht University
Known forDiscovering cause of chronic myelogenous leukemia
AwardsLouis-Jeantet Prize for Medicine (1995)[1]
Scientific career
InstitutionsErasmus University Rotterdam
Dirk Bootsma (23 May 1936 – 5 October 2020) was a Dutch geneticist. He was a professor at the Erasmus University Rotterdam between 1969 and 2002. He and his research group discovered the cause of chronic myelogenous leukemia and furthered the understanding of the nucleotide excision repair.
Bootsma was born on 23 May 1936. He started his study of biology at Utrecht University in September 1953. He did his first DNA-research under professor Winkler. In 1965 he obtained his PhD from Leiden University. In the late 1960s Bootsma performed his compulsory military service at the Medical-Biological Laboratory of the Netherlands Organisation for Applied Scientific Research (TNO). There, he researched the influence of X-radiation on chromosomes in living cells.
After obtaining his PhD, Bootsma joined the newly found department of cell biology and genetics at the Erasmus University Rotterdam. In 1969, he became a professor of genetics. After recombinant DNA became available, Bootsma and his department made use of this technology. In 1974 he organized the second Human Gene Mapping Conference in Noordwijkerhout. Bootsma later lost his interest in gene mapping. He then turned to cancer research, relying on his earlier experiences at TNO. He focused on mechanisms that repaired DNA, especially in rare forms of skin cancer, and discovered several proteins in this field. Bootsma had a special interest in chromosome 22, which was recently discovered to be involved in chronic myelogenous leukemia. In 1982, the research team of Bootsma discovered the cause of this specific type of blood cancer: two broken chromosomes (9 and 22) which were attached mistakenly reattached to the other, leading to the Philadelphia chromosome.
Another topic on which Bootsma furthered research from his time at TNO was DNA repair. He set up research into genetic disorders, especially xeroderma pigmentosum (XP). For this research Bootsma used human cells, being one of the first in the Netherlands to do so. With the developing of technology, especially the possibility to insert foreign DNA into humans and the discovery of recombinant DNA, Bootsma was able to further his study of XP. In 1984 his group was able to clone the repair gene ERCC1. When ERCC3 was also cloned this led to a solution for DNA repair in XP-patients by inserting them in their fibroblasts, leading to an overall furthered the understanding of the nucleotide excision repair.
Bootsma retired in October 2002, he was succeeded as group research leader by Jan Hoeijmakers .
Bootsma died on 5 October 2020, aged 84.
Honours and distinctions
Bootsma was elected a member of the European Molecular Biology Organization in 1976. He was elected a member of the Royal Netherlands Academy of Arts and Sciences in 1983. Bootsma was elected a member of the Academia Europaea in 1991.
Bootsma and Jan Hoeijmakers won the 1995 Louis-Jeantet Prize for Medicine. In 1996 Bootsma held the Rogier Soher Lecture of the International Agency for Research on Cancer. In 2000 he won the Mauro Baschirotto Award of the European Society of Human Genetics. In 2009 Bootsma's discovery of the relation between chronic myelogenous leukemia and the Philadelphia chromosome was incorporated in the Dutch canon of medicine.
Dirk Bootsma
Dirk Bootsma Dirk Bootsma
Dirk Bootsma Dirk Bootsma Dirk Bootsma
Dirk Bootsma search
searchDirk Bootsma search
Dirk Bootsma dies
Dirk Bootsma funeral details
Dirk Bootsma funeral notice
Dirk Bootsma funeral service
Dirk Bootsma life story
why did Dirk Bootsma die?
who was Dirk Bootsma married to?
who were Dirk Bootsma's children?
was Dirk Bootsma gay?
where did Dirk Bootsma live?
where did Dirk Bootsma work?
where did Dirk Bootsma go to school?
what was Dirk Bootsma's criminal history?
what was Dirk Bootsma's phone number?
what was Dirk Bootsma's email address?
what was Dirk Bootsma's social security number?
what was Dirk Bootsma's blood type?
what was Dirk Bootsma's eye color?
what was Dirk Bootsma's favorite food?
what was Dirk Bootsma's favorite movie?
what was Dirk Bootsma's favorite band?
what was Dirk Bootsma's favorite colour?
what crimes was Dirk Bootsma convicted of?
who attended Dirk Bootsma's funeral?
how tall was Dirk Bootsma?
how old was Dirk Bootsma?
how much did Dirk Bootsma weigh?
how much money did Dirk Bootsma have?
what was Dirk Bootsma's net worth?
was Dirk Bootsma ever married?
what was Dirk Bootsma's IQ?
what was the reason for Dirk Bootsma's death?
was Dirk Bootsma 's nickname?
is Dirk Bootsma really dead?
when did Dirk Bootsma die?
where did Dirk Bootsma die?
what was the cause of Dirk Bootsma's death?
when is Dirk Bootsma's funeral?
where will Dirk Bootsma's funeral be held?
Dirk Bootsma bereavement
Dirk Bootsma casualty
Dirk Bootsma cessation
Dirk Bootsma curtains
Dirk Bootsma darkness
Dirk Bootsma decease
Dirk Bootsma demise
Dirk Bootsma departure
Dirk Bootsma destruction
Dirk Bootsma dissolution
Dirk Bootsma downfall
Dirk Bootsma dying
Dirk Bootsma end
Dirk Bootsma ending
Dirk Bootsma eradication
Dirk Bootsma euthanasia
Dirk Bootsma exit
Dirk Bootsma cause of death
Dirk Bootsma how she died
Dirk Bootsma when she died
Dirk Bootsma where she died
Dirk Bootsma how he died
Dirk Bootsma when he died
Dirk Bootsma where he died
Dirk Bootsma suicide
Dirk Bootsma death
Dirk Bootsma by her own hand
Dirk Bootsma by his own hand
Dirk Bootsma gunshot
Dirk Bootsma murder
Dirk Bootsma robbery
Dirk Bootsma stabbing
Dirk Bootsma car accident
Dirk Bootsma drowning
Dirk Bootsma paper cut
Dirk Bootsma accident
Dirk Bootsma crash
Dirk Bootsma depression
Dirk Bootsma mental illness
Dirk Bootsma cancer
Dirk Bootsma expiration
Dirk Bootsma extermination
Dirk Bootsma extinction
Dirk Bootsma fatality
Dirk Bootsma finis
Dirk Bootsma finish
Dirk Bootsma grave
Dirk Bootsma heaven
Dirk Bootsma loss
Dirk Bootsma mortality
Dirk Bootsma necrosis
Dirk Bootsma obliteration
Dirk Bootsma oblivion
Dirk Bootsma paradise
Dirk Bootsma parting
Dirk Bootsma passing
Dirk Bootsma quietus
Dirk Bootsma release
Dirk Bootsma repose
Dirk Bootsma ruin
Dirk Bootsma ruination
Dirk Bootsma silence
Dirk Bootsma sleep
Dirk Bootsma termination
Dirk Bootsma tomb
Dirk Bootsma eternal rest
Dirk Bootsma grim reaper
Dirk Bootsma passing over
Dirk Bootsma obituary
Dirk Bootsma legacy
who killed Dirk Bootsma?
what killed Dirk Bootsma?
where was Dirk Bootsma killed?
where was Dirk Bootsma murdered?
how old was Dirk Bootsma?
how dead was Dirk Bootsma?
Dirk Bootsma سبب الوفاة
Dirk Bootsma doodsoorzaak
Dirk Bootsma cause de décès
Dirk Bootsma Todesursache
Dirk Bootsma causa di morte
Dirk Bootsma 死
Dirk Bootsma причина смерти
Dirk Bootsma causa de la muerte
Dirk Bootsma dödsorsak
About cookies on this site
We use cookies to collect and analyse information on site performance and usage, to provide social media features and to enhance and customise content and advertisements.Learn more